Pathways to Precision Medicine. From Rare to Common Diseases

Precision Medicine capitalizes on both conceptual paradigm shifts and technological disruptive advancements to reach a more integrative and holistic definition of health and disease states. It relies on both biological individuality and populational knowledge which mutually nurture each other. It stands on two main pillars : data generation and data modeling. High-throughput technologies (sensors, imaging and omits) allow now the retrieval of comprehensive, dynamic and holistic biological information, whereas computational capabilities enable high-dimensional data modeling and, therefore, accessible and clinically actionable information.
The aim of this book, mainly inspired by the talks given atthe Pathways to Precision Medicine international symposium, is to raise awareness in the medical and scientific community and institutional officials about the opportunities and challenges of tomorrow's healthcare. A new medicine that aspires to be integrative, predictive and precise by embracing the new technologies that are deeply changing medical practice.

Dans ce volume, les acteurs internationaux de la "médecine de précision" en présentent les principes généraux. Il s'agit d'une approche de la prévention et du traitement des maladies tenant compte des variations individuelles en matière de génétique, d'environnement et de mode de vie. En fournissant le bon traitement au bon patient au bon moment, cette approche permet une gestion ou une prévention individualisée des maladies.